Serum Levels of the Adipokine Chemerin in Relation to Renal Function

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Serum Levels of the Adipokine Chemerin in Relation to Renal Function

OBJECTIVE To investigate serum levels of the adipokine chemerin in patients on chronic hemodialysis (CD) as compared with control patients with a glomerular filtration rate (GFR) >50 ml/min. RESEARCH DESIGN AND METHODS Chemerin was quantified by ELISA in control patients (n = 60) and CD patients (n = 60) and correlated with clinical and biochemical measures of renal function, glucose, and lip...

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Chemerin and renal function Serum levels of the adipokine chemerin in relation to renal function Running Title: Chemerin and renal function

This is an uncopyedited electronic version of an article accepted for publication in Diabetes Care. The American Diabetes Association, publisher of Diabetes Care, is not responsible for any errors or omissions in this version of the manuscript or any version derived from it by third parties. The definitive publisherauthenticated version will be available in a future issue of Diabetes Care in pr...

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Serum Levels of the Adipokine FGF21 Depend on Renal Function

OBJECTIVE To investigate renal elimination of the adipokine fibroblast growth factor 21 (FGF21) by determining circulating FGF21 levels in patients on chronic hemodialysis (CD) as compared with control subjects with a glomerular filtration rate (GFR) >50 ml/min. RESEARCH DESIGN AND METHODS FGF21 was determined by enzyme-linked immunosorbent assay in control (n = 60) and CD (n = 60) patients a...

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Serum Levels of the Adipokine Progranulin Depend on Renal Function

OBJECTIVE Progranulin has recently been introduced as a novel adipokine inducing insulin resistance and obesity. In the current study, we investigated renal elimination, as well as association of the adipokine with markers of the metabolic syndrome. RESEARCH DESIGN AND METHODS Progranulin serum levels were quantified by enzyme-linked immunosorbent assay and correlated to anthropometric and bi...

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Serum levels of adipokine retinol-binding protein-4 in relation to renal function: response to Ziegelmeier et al.

OBJECTIVE Retinol-binding protein (RBP)-4 was recently identified as an adipokine that induces insulin resistance. In the current study, we investigated RBP-4 serum levels in diabetic and nondiabetic patients on chronic hemodialysis (CD) compared with control subjects with a glomerular filtration rate >50 ml/min. The majority of the diabetic subjects used oral hypoglycemic agents or insulin. ...

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2009

ISSN: 0149-5992,1935-5548

DOI: 10.2337/dc09-1351